Program description

The Cheburator software was developed for automated data processing and calculation of the IC50 values from the in vitro screening tests. The results of these in vitro drug screening assays are commonly expressed as inhibitory concentration 50% (IC50): the concentration of the tested agent that inhibits the proliferation of the cancer cell population to 50% of the theoretically possible effect (absolute IC50) or maximum effect practically achieved by the drug (relative IC50). The amount of data obtained during a screening test requires extensive processing and calculation. This software can substantially reduce the amount of time spent by scientific staff on data evaluation and can be used in numerous laboratories working in the area of the in vitro drug screening programs.

Publication describing the software:

Nevozhay D. Cheburator software for automatically calculating drug inhibitory concentrations from in vitro screening assays. PLoS One, 9:9 (2014), e106186

Download

Download latest Cheburator 1.2.0 version + sample files + documentation (zipped archive)
Download latest Cheburator 1.2.0 source files (zipped archive)
Download DMath 0.90 library for Pascal (zipped archive), originally downloaded from its homepage
Download Cheburator user manual (pdf, requires free Adobe Acrobat Reader)
Download sample report produced by Cheburator (pdf, requires free Adobe Acrobat Reader)

Contact

The software is freely available for academic use, but a license is required for commercial use. Please send all inquiries or suggestions concerning this software to the author:

Dmitry Nevozhay M.D., Ph.D.,
E-mail: dnevozhay@gmail.com

Screenshots

Main window of the Cheburator	Options
Graphs	Page with the results and calculated IC50 values

© Copyright 2007-2014, Dmitry Nevozhay